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KPV 10mg

KPV 10mg

Certificate of Analysis

Third-party tested for 99% purity, ID, quantity.

Certificate of Analysis

Third-party tested for endotoxins

2606AFL103
2606AFL103
2606AFL103
2606AFL103
10 mg

Synthetic tripeptide. Reference material for in vitro laboratory research use only.

Compound KPV (?-MSH 11–13)
CAS 67727-97-3
Sequence (1-letter) KPV
Sequence (3-letter) Lys-Pro-Val
Molecular formula C16H30N4O4
Molecular weight 342.44 g/mol
Net content 10 mg per vial (gross fill; actual content per lot COA)
Form Lyophilized powder
Storage ?20 °C, sealed, dry, protected from light
Testing Identity and purity verified by third-party HPLC analysis; a lot-specific Certificate of Analysis is provided with each order.

Research Use Only. Not a drug, supplement, or food. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

KPV 10mg Structure

Chemical Structure Diagram

CAS: #67727-97-3
Formula: C??H??N?O?
Molecular Weight: 388.4 g/mol
PubChem ID: 16129619

Research Findings

KPV has been extensively studied in cytokine signaling research, with investigations focusing on NF-?B pathway modulation, epithelial signaling models, barrier dynamics, and immune modulation in various experimental systems. Studies examine both its unique transporter-mediated delivery and potent cytokine-modulating mechanisms.

Key Areas of Research:

  • Cytokine: NF-?B, MAPK, suppression

  • Epithelial: Mucosal signaling, modeling

  • Barrier: Tight junction, permeability, integrity

  • Immune: Peptide-receptor, macrophage, T-cell

Together, these investigations demonstrate KPV’s multifaceted cytokine-modulating actions through PepT1-mediated uptake and direct intracellular signaling modulation. As a minimal bioactive sequence, KPV provides a research framework for examining peptide-based cytokine mechanisms, epithelial immune signaling, and barrier dynamics in diverse experimental models.

Dalmasso et al., Gastroenterology, 2008

Brzoska et al., Inammation Research, 2008

Getting et al., Journal of Pharmacology and Experimental Therapeutics, 2003

References

Dalmasso G. et al. (2008). PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology, 134(1):166-178.

Brzoska T . et al. (2008). ?-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Inflammation Research, 57(1):14-22.

Getting S.J. et al. (2003). The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage. Journal of Pharmacology and Experimental Therapeutics, 306(2):631-637.

Our Process

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STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our
U.S. facility.

STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our
U.S. facility.

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Frequently Asked Questions

Everything you need to know about our products and processes.

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Each vial contains exactly what’s shown on the label. For example, a 10mg vial has exactly 10mg of lyophilized peptide. Researchers can divide it into smaller portions—like four 2.5mg measurements—but the total amount remains 10mg.

 
Peptides are supplied as lyophilized powder. They do not come reconstituted, and any extra supplies must be sourced separately for research applications.
 
 
In lyophilized powder form, peptides stay stable for up to 2 years. After reconstitution, it should be refrigerated and is generally stable for up to 2 months.
 
 
Products from us do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.
 
 
Lyophilized peptides should be stored away from heat and light. Once reconstituted, they must be refrigerated to maintain stability and efficacy.