Third-party tested for 99% purity, ID, quantity.
Third-party tested for endotoxins
Synthetic tetrapeptide. Reference material for in vitro laboratory research use only.
| Compound | Epitalon (AEDG tetrapeptide) |
| CAS | 307297-39-8 |
| Sequence (1-letter) | AEDG |
| Sequence (3-letter) | Ala-Glu-Asp-Gly |
| Molecular formula | C14H22N4O9 |
| Molecular weight | 390.35 g/mol |
| Net content | 10 mg per vial (gross fill; actual content per lot COA) |
| Form | Lyophilized powder |
| Storage | ?20 °C, desiccated, protected from light |
| Testing | Identity and purity verified by third-party HPLC analysis; a lot-specific Certificate of Analysis is provided with each order. |
Research Use Only. Not a drug, supplement, or food. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
Epithalon has been evaluated across chronological aging, oncology, neuroendocrine, and ophthalmological models, with reports of activity in telomere elongation pathways, melatonin synthesis upregulation, and free radical scavenging. Research also highlights its potential roles in restoring regular T-cell functions and preserving cellular structural dynamics within compromised retinal tissue models.
Key Areas of Research:
Chronological: Telomerase activation, telomere length extension tracking, cellular replication boundaries
Endocrine: Pineal gland secretion balancing, circadian rhythm normalization, nocturnal melatonin regulation
Oncology: Spontaneous tumor generation metrics, antimetastatic properties, chromatin structural opening
Ophthalmological: Retinal degradation deceleration, visual cortex cell survival, retinitis pigmentosa tracking
Together, these investigations demonstrate Epithalon’s capacity to interact directly with genetic regulatory mechanisms. As a short-chain tetrapeptide, it provides a stable research framework for examining cellular lifespan, DNA protective mechanics, and systemic endocrine decline. By influencing pathways related to telomere maintenance and melatonin balance, Epithalon offers a versatile platform for research into programmatic cellular longevity and resilience within experimental paradigms.
https://pubmed.ncbi.nlm.nih.gov/12455115/
Khavinson V.Kh. et al. (2003). Peptide regulation of aging: 35-year experience in research and clinical application. Medical Subject Headings (MeSH). URL: https://pubmed.ncbi.nlm.nih.gov/14587118/
Anisimov V.N. et al. (2001). Effect of the synthetic peptide Epitalon on life span and spontaneous tumorigenesis in female Swiss mouse models. Mechanisms of Ageing and Development, 122(15):1755-1768. URL: https://pubmed.ncbi.nlm.nih.gov/11557288/
Khavinson V.Kh. et al. (2002). Telomerase activity-activating effect of the peptide Epitalon in human somatic cells. Bulletin of Experimental Biology and Medicine, 133(6):590-592. URL: https://pubmed.ncbi.nlm.nih.gov/12455115/
STEP 1
Precision Lyophilization
Manufactured in a controlled U.S. facility under strict compounding standards.
STEP 2
Verified Purity
Every batch third-party tested with HPLC and mass spectrometry.
STEP 3
Same-Day Fulfillment
Orders dispatched same-day from our
U.S. facility.
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