GLP-3

Quantity

Clear

Certificate of Analysis

Third-party tested for 99% purity, ID, quantity.

Certificate of Analysis

Third-party tested for endotoxins

10 mg

Synthetic lipidated peptide. Reference material for in vitro laboratory research use only.

CAS	2381089-83-2
Sequence	Published renderings are inconsistent; see lot Certificate of Analysis
Molecular formula	C₂₂₁H₃₄₂N₄₆O₆₈
Molecular weight	4731.33 g/mol
Net content	10 mg per vial (gross fill; actual content per lot COA)
Form	Lyophilized powder
Storage	?80 °C for long-term; ?20 °C sealed, dry, protected from light, under inert gas
Note	Published sequence renderings are inconsistent; identity per lot COA.
Testing	Identity and purity verified by third-party HPLC analysis; a lot-specific Certificate of Analysis is provided with each order.

Research Use Only. Not a drug, supplement, or food. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

GLP-3 Structure

CAS: #2381089-83-2
Molecular Formula: C???H???N??O??
Molecular Weight: 4731.33 g/mol
PubChem ID: 171390338

Research Findings

GLP-3 has been investigated for its interactions with three major metabolic receptors: GLP-1R, GIPR, and GCGR. Experimental and clinical research has examined how simultaneous engagement of these pathways may influence metabolic signaling, energy regulation, glucose-related processes, and broader physiological pathway dynamics.

Key Areas of Research:

GLP-1 Signaling: Incretin receptor activity and metabolic pathway regulation
GIP Signaling: Glucose-dependent insulinotropic signaling and energy-related processes
Glucagon Signaling: Glucagon receptor activity and energy homeostasis
Metabolic: Multi-pathway signaling, energy regulation, and systemic metabolic dynamics

Together, these findings make GLP-3 a notable compound for investigating coordinated receptor signaling across multiple metabolic pathways. Its triple-agonist profile provides a research framework for studying how GLP-1, GIP, and glucagon receptor systems interact and contribute to broader pathway dynamics within controlled experimental settings.

Coskun T. et al., Cell Metabolism, 2022

References

Coskun T. et al. (2022). LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist for glycemic control and weight loss.

Jastreboff AM. et al. (2023). Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial.

Sanyal AJ. et al. (2024). Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial.

MedChemExpress — Retatrutide (LY3437943). Compound identity, CAS number, molecular formula, molecular weight, and receptor activity data.

GLP-3 Research Material — Identity and Research Context. Published research identity and reference information for CAS 2381089-83-2.

Our Process

STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our
U.S. facility.

STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our
U.S. facility.

Email us, our dedicated team is here to help

Reach out and get a response within minutes.

Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?

Each vial contains exactly what’s shown on the label. For example, a 10mg vial has exactly 10mg of lyophilized peptide. Researchers can divide it into smaller portions—like four 2.5mg measurements—but the total amount remains 10mg.

Are additional supplies needed?

Peptides are supplied as lyophilized powder. They do not come reconstituted, and any extra supplies must be sourced separately for research applications.

How long does a vial last?

In lyophilized powder form, peptides stay stable for up to 2 years. After reconstitution, it should be refrigerated and is generally stable for up to 2 months.

Does the product come with instructions?

Products from us do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

How should I store these products?

Lyophilized peptides should be stored away from heat and light. Once reconstituted, they must be refrigerated to maintain stability and efficacy.